Thursday, August 30, 2007

How The Bird Flu Virus Lives And Spreads

Bird flu is a serious and dangerous virus. With so much controversy over this deadly disease, it is a good idea to have some kind of idea what you are up against. Knowing how the virus lives and spreads makes it easier to protect yourself from infection.

First, it should be understood that bird flu is much like the other strains of influenza. Like the flu that goes around every year, bird flu is transmitted from the exchange of the virus through droplets of saliva, mucus, or other excretions. However, bird flu is not transmitted from human contact, but through the handling or ingestion of infected poultry. It is more common for people to be impacted by bird flu that handle birds for agricultural purposes or eat infected fowl that is not properly handled.

The virus lives within poultry and survives in the feces of the animal for several days, if not weeks. Therefore, regular contact with birds, especially in dense populations, increases the possibility of contracting the disease. To avoid infection, limit contact with potentially dangerous poultry.

It should also be clear that this particular virus was not always a threat to humans. Prior to 1997, there were no known cases of H5N1, the deadly strain of bird flu, infecting humans. Since the virus first came to pass in the early 1900's, it has mutated and transformed into a different form. This mutation is vital to the ongoing vitality of influenza and is the primary source for the concern surrounding H5N1. The virus continually manipulates itself to bypass treatment techniques and survive in varying environments.

Once the virus is transmitted to a person, it is incredibly interesting what takes place. There are two factors within the immune system that contribute to the devastation of the virus. First, the virus causes an exaggerated response in cytokines, hormones that regulate the immune system. This increase makes the immune system unstable and actually has a negative effect on the body itself, as well as making fighting infection difficult. Secondly, other aspects of the immune system are suppressed, allowing the virus to run rampant within the body.

Since the virus is not bacterial in nature, antibiotics are ineffective in treating the disease. In many illnesses, antibiotics are administered, which suppress the immune system and fight the infection; however, this is not an option due to the nature of bird flu; therefore, the most effective treatment is prevention.

Sarah is an acclaimed writer on medical matters, and has written extensively on the subjects of Attention Deficit Disorder, Bird Flu and Cohn's Disease. For more of her articles, go to http://www.imedicalvillage.com now.

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Why Bird Flu Is Not A Pandemic

Most people are aware of the threat of bird flu and the possibility of it creating a pandemic, a worldwide epidemic of an infectious disease breaking out and affecting a large geographic region. Although the virus affects an extensive geographic region, this virus has not yet reached pandemic proportions.

According to the World Health Organization, in order for a pandemic to occur, three conditions must be met: the emergence of a disease new to a population, the agent affects humans and causes serious illness, and the agent spreads easily and sustainably among humans.

The first of these three, "the emergence of a disease new to a population" has occurred. Although bird flu is in no way a new disease, as it was first identified in the early 1900's, it was not infectious to humans until the late 1990's. Therefore, this particular strain has emerged "new to a population", being the human population, which was previously unaffected by the disease.

Likewise, the second criterion has been met, "the agent affects humans and causes serious illness". The virus has infected 131 people and killed 68. Therefore, the severity of the disease is apparent. H5N1 causes an exaggerated response in cytokines, hormones that regulate the immune system, therefore, limiting the effectiveness of the body's ability to fight the infection. This virus is also partially resistant to other cells of the immune system, making it especially resilient.

The third condition has not been met, however. At this point, the virus does not spread easily and sustainably among humans. Currently, the H5N1 virus is only transmitted from poultry to humans, and is not able to pass through human contact. Unfortunately, the virus is mutating and may be able to do so in future months, increasing the speed and efficiency in which it spreads.

Human to human transmission has been suspected, though not confirmed. Several isolated cases in which the cause of infection was not clear have prompted questions of the virus being passed through human contact. In particular, cases of nurses becoming infected after treating patients, children being infected with no poultry contact, and parents being infected after treating children with the disease. However, until confirmation is attainable that the virus has mutated to the point human transmission is possible, the third criterion will not be satisfied and H5N1 will not be classified as a pandemic. Likewise, the fatality rate will also have to increase to change the classification of bird flu.

Sarah is an acclaimed writer on medical matters, and has written extensively on the subjects of Attention Deficit Disorder, Bird Flu and Cohn's Disease. For more of her articles, go to http://www.imedicalvillage.com now.

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Bird Flu: Diagnosis

Central to the problem of dealing with bird flu is diagnosis. A number of upper respiratory infections have similar symptoms?at least at the onset of the illness, including the common cold, seasonal influenza, and bird flu. Seasonal flu and bird flu have almost identical symptoms?including fever, cough, malaise (feeling unwell), nausea, vomiting, and diarrhea. This is, needless to say, a gigantic problem in accurately diagnosing bird flu?which is critical to beginning appropriate treatment as well as initiating infection control procedures and public health measures.

Currently, accurate testing for bird flu and other vial infections that can cause similar symptoms is difficult and requires specialized testing. This testing is time consuming and only available in specialized reference laboratories, which are few and far between. Fortunately, this may change in the near future.

According to Richard Janeczko, Ph.D., executive vice-president and chief scientific officer, Tm Bioscience, located In Toronto, Canada, is feverishly working to complete the final stage of development of an amazing test?not only for bird flu, but for more than 15 other viral infections (including severe acute respiratory syndrome or SARS), many of which can mimic the symptoms of bird flu (personal communication). (Tm Bioscience is a DNA-based diagnostics company developing a suite of genetic tests. Tm Bioscience?s product pipeline includes tests for genetic disorders, drug metabolism, and infectious diseases.

The test, called the Multiplexed Respiratory Test, discriminates influenza A from influenza B and identifies the H5-subtype of influenza A (bird flu is ?H5N1?) from all other H subtypes. In addition, it can identify almost all the other common?and some uncommon?viruses that cause influenza-like illnesses. This is extremely important in managing patients, communities and economic issues. Other tests have lower clinical sensitivities and specificities which can lead to both false positives and false negatives.

By incorrectly identifying an outbreak as due to H5N1, patients could be treated with anti-virals unnecessarily (thus raising the chances of selecting for drug-resistant strains), unneeded vaccination programs in asymptomatic individuals could be initiated, and damage to local and national economies?through such measures as culling of commercial poultry operations?could occur. Conversely a false-negative test result could lead to catastrophic outcomes, including a pandemic.

The assay utilizes swab specimens taken from the nose and takes less than 5 hours to perform. It was developed for use as a diagnostic tool and for infection control in hospitals. The assay has been slated for expedited review by the Food and Drug Administration (FDA), and TM Bioscience is hoping to have an FDA-cleared test available by the end of January 2006. If this assay delivers what it claims, it will have huge applicability on a global basis and save many lives.


Bradford Frank, M.D., M.P.H., M.B.A. The Frank Group. P.O. Box 138 Lakewood, NY 14750 http://www.AvoidBirdFlu.com

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Where Are The Greatest Risk Area For Bird Flu?

With Bird Flu in the news, people are wondering where it may be safe to avoid this deadly virus. While the answer to this question may be very simple now, in a few weeks or months, it may be a different story.

The first outbreak of the deadly strain of bird flu in humans was in Hong Kong in 1997. A major outbreak then occurred in January of 2004 in Vietnam and Thailand that resulted in the virus popping up in most of Asia, Europe, and the Middle East. Recently, a low pathogenic form of H5N1, the dangerous form of bird flu, surfaced in Canada. From this, it may be assumed that southern parts of North America, South America, and other countries distanced from Asia are safe. However, with the track record of this virus, that may not be the case.

Without a doubt, the area of greatest risk for Bird Flu currently is Vietnam, where the largest number of infections and death has occurred. Any area in Asia with a large poultry population, from farming or agriculture, is at risk, as consuming infected meat has been a primary cause of becoming infected. On the same note, many countries in Asia, Europe, and recently the Middle East, should be concerned with the possibility of ingested infected poultry. As migratory birds may also carry the disease, it may be extend over widespread areas as well as from agricultural sources.

Likewise, considering the rapid spread of bird flu, the case in Canada should be of concern for residents of North America as well; in less than two years, Asia and Europe were consumed with the disease. Although the case in Canada was a low pathogenic form of H5N1, meaning it is less dangerous, the fact that it made its way to the continent should not be taken lightly and the possibility of the virus spreading south is a very serious threat.

As long as bird flu is being transmitted from poultry to humans, and not from human to human contact, the areas of concern will surround large poultry populations, from wild or agricultural birds. However, if the strain mutates and is passed from human to human, the risk area will grow rapidly and be concentrated in places with high or dense populations. Likewise, areas of particular concern will be those with limited medical care. Areas with advanced medicine that may be able to produce a vaccine may not be as devastated by the mutated strain of the virus.


About the Author: Sarah is an acclaimed writer on medical matters, and has written extensively on the subjects of Attention Deficit Disorder, Bird Flu and Crohn?s Disease. For more of her articles, go to http://www.imedicalvillage.com now. Click here now and re

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Key Facts About Bird Flu

Bird flu was first identified in the early 1900's and has since spread worldwide. Also known as avian influenza, this virus has caused considerable concern due to the mutation of a particular strain of the disease. Although this virus previously only infected birds and other types of animals, namely pigs, since 1997, it has also been known to infect humans.

The strain of the disease to cause so much concern is H5N1. These are simply numbers and letters that represent the subtype of this particular strain, 1 of 144 influenza subtypes. Not only has the virus caused an epidemic in poultry, but it has recently been feared to be leading to a pandemic, or worldwide epidemic, in humans.

While the virus was first identified in humans in 1997, it was not until 2004 that the spread became of great concern. At that time, a major outbreak occurred in Vietnam and Thailand, which spread to ten countries and regions of Asia within weeks and caused the death of 23 people. Within three months the outbreak was contained after the slaughter of tens of millions of potentially infected birds. However, the damage was already done and the virus had spread across Asia to lead to additional outbreaks. Since that time, H5N1 has spread throughout Asia, Europe, and the Middle East, and a low pathogenic form of the virus was identified in Canada on November 19, 2005. Currently, 131 humans have been infected with the virus, resulting in 68 deaths. However, it is feared this number will only increase with the ongoing spread of the disease.

The primary concern surrounding H5N1 is its mutation and ability to infect humans. As of yet, the virus has been spread from poultry to humans, and human to human transmission has only been suspected but not confirmed. Once the virus mutates further, it will easily be passed through humans, causing the disease to spread rapidly. Influenza pandemics, or worldwide epidemics, have caused a great number of deaths in the past, including the Spanish Flu which killed 50 million people in 1918. This is the ultimate concern with the mutation and spread of H5N1.

At this time, the primary cause of infection has been due to the consumption or handling of diseased poultry. Unfortunately, there have been a very few cases that were not easily explained, and therefore, human to human transmission was suspected. However, this has not been confirmed in any of the cases of H5N1 infection.

About the Author

Sarah is an acclaimed writer on medical matters, and has written extensively on the subjects of Attention Deficit Disorder, Bird Flu and Crohn's Disease. For more of her articles, go to http://www.imedicalvillage.com now. Click here now and re

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How Great Really Is The Risk Of Catching Bird Flu?

With bird flu being on every television station and newspaper, it is easy to get caught up in the panic surrounding this new viral outbreak. However, do you find yourself wondering if this should really be a concern? Do you remember when everyone was becoming hysterical over the likelihood of killer bees sweeping the United States? I do not know about you, but I have yet to be chased down by an African Honey Bee. So, what are your real chances of catching bird flu?

To answer the question as asked: it is not very likely for you to catch bird flu right now. Of course, they key to this statement is ?right now?. Currently, an outbreak of bird flu is occurring in Asia. Over 100 people have contracted the virus and over half have died. Also, as of yet, the virus can only be transmitted to humans from infected birds. Therefore, when a person becomes infected, they can not pass the virus on to others. However, change may be on the horizon.

Many experts believe, within time, the bird flu virus will mutate and be able to be passed from human to human. This is actually a likely occurrence, as influenza strands are known for their adaptability. With every human the virus infects, it becomes more likely to transform. When this happens, the numbers affected by bird flu will increase exponentially.

Even with limited means of being transmitted, avian influenza, or bird flu, has spread across Asia rapidly. Imagine how quickly it will affect the various parts of the world, once it is carried by humans over oceans, in planes and on boats. Densely populated areas will see the worst part of the virus, as close human contact is a breeding ground for disease.

Interestingly enough, this is not the first time an influenza virus threatened massive death. In 1918, the Spanish Flu killed 50 to 100 million people; in 1957, the Asian Flu killed 1 to 1.5 million; and in 1969, the Hong Kong Flu killed roughly 1 million people. Considering this seems to happen every few years, is it that far fetched it could be on its way again? Is history repeating itself? The answer can only be answered in time. If the virus does not mutate, everyone could all worked up over nothing. However, if it does and a pandemic occurs as expected, up to 30% of the world?s population could be infected.


About the Author: Sarah is an acclaimed writer on medical matters, and has written extensively on the subjects of Attention Deficit Disorder, Bird Flu and Crohn?s Disease. For more of her articles, go to http://www.imedicalvillage.com now. Click here now and re

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Wednesday, August 29, 2007

How To Lower Your Risk Of Catching Flu (Including Bird Flu)

Influenza is in no way a new ailment to plague the people of the world. However, a new deadly strand of the virus has everyone running for cover. How do you avoid catching flu, including the dangerous bird flu that threatens so many?

First, it should be explained that bird flu, also known as avian influenza, is a virus much like the regular flu we are accustomed to. It is transmitted in much the same way, through droplets of saliva and mucus. However, bird flu is currently only transmitted from infected birds to humans and can not be passed from human to human like the regular flu. The main concern arises with bird flu as it is expected to mutate and at some point be transmitted by humans as well. Until this takes place, bird flu is only passed from infected birds to humans by way of direct contact with the animal or its feces.

The current outbreak of bird flu is taking place in Asia; therefore, there is little concern of catching the virus unless you are in that region and handling fowl. However, once the virus mutates it will be transmitted much like the standard flu and may be avoided in much the same way.

The obvious first step in lowering your risk of catching the virus is being administered a vaccine. There is currently not a vaccine for the dangerous strand of influenza, but one is being developed. With any luck one will be produced prior to any widespread contamination of the virus.

Another option is one utilized in most regular flu cases - taking antiviral medication, such as Tamiflu. These are expected to be effective on the dangerous strand of influenza as well as the regular flu virus. However, for this treatment to be useful, it must be administered early in the virus, typically within two days of showing symptoms. This and other drugs do not cure the virus, but instead lessen the effects of the symptoms. They may, however, prevent the virus from becoming severe.

The most effective way to avoid catching the flu, the regular flu as well as the bird flu, is prevention. Proper hygiene reduces the risk of the spread of influenza. Simple things, like washing your hands and avoiding close contact with sick people, may be your best technique in lowering your risk of becoming infected. Utilizing hand sanitizer is also a useful option.


About the Author: Sarah is an acclaimed writer on medical matters, and has written extensively on the subjects of Attention Deficit Disorder, Bird Flu and Crohn?s Disease. For more of her articles, go to http://www.imedicalvillage.com now. Click here now and re

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Don't Count On A Bird Flu Vaccine, Count On A Nanomask

You've no doubt seen the news reports about Bird Flu, a deadly airborne virus. And you no doubt feel at risk and vulnerable.

A Bird Flu vaccine is months and months away from production, and production will be a problem since health officials believe it will take at least 1 year to make enough for all citizens. Even then, it may not be effective, since it was based on an earlier seed of the virus. Bird Flu, or H5N1, mutates rapidly. Today, Bird Flu is something entirely different than when it was first discovered.

But there is one, off-the-shelf, device that will protect you and your family against Bird Flu, SARS, and ordinary flu, right now. It's called NanoMask, manufactured by a company that originally was tasked to make a better biomask for our military troops.

Why is a filter mask the best tool you can have against Bird Flu? Because of its new nano-technology. A NanoMask isn't just an ordinary N95 mask like you see in hospitals or on construction sites.

N95 masks are not effective against any particulate, virus, or bacteria smaller than .3 microns, and thus a waste of money if you buy an N95 mask for the purpose of blocking H5N1 or any influenza virus. Even hospitals realize this and are now ordering NanoMasks.

Examine the table below showing virus sizes, so you can judge for yourself how effective the NanoMask is. The abbreviation nm means nanometer, which is one billionth of a meter. N95 can only filter out material greater in size than .3 microns, which equal to 300 nanometers.

Every virus you see in the table below is smaller than 300 nanometers, therefore, N95's are useless against these viruses.

Virus (Description) | Size

Bacteriophage (MS) | 220nm
Hepatitis | 24nm - 30nm
Adenovirus | 70nm HIV
(AIDS) | 80nm
Cytomegalovirus | 100nm
Orthomyxovirus | 120nm
Coronavirus (SARS) | 80nm - 160nm

According to Nelson Laboratories of Salt Lake City, an independent testing lab of such filters, Bacteriophage MS-2 is the recognized standard testing organism for many filters. Being one of the smallest used viruses at 20nm, it is able to give a higher challenge to the filter media.

NanoMask has been tested down to 27 nanometers or .027 microns. Good enough to stop H5N1, SARS, and other viruses listed in the Virus Size Table above, as well as ordinary influenza.

The unique design and enhanced facial seal allows the NanoMask to overcome the most critical failing of typical N95 masks: an inability to effectively seal against the face and filter inhaled and exhaled breath that will typically follow the path of least resistance - around the sides of the mask.

The president of Emergency Filtration, Doug Beplate, told this author that the primary reason NanoMasks are so successful in stopping viruses is their unique nanoparticle coating on each filter. Beplate said, "The nanoparticle coating joins with chlorine particles to achieve an arrest and eradication of undesirable agents." In other words, biohazardous particulates like H5N1 are not only blocked, but destroyed, thanks to the nanoparticle coating.

A traditional filter without the nanoparticle coating, like N95, would turn into a breeding ground for a virus or bacterial agent. Thus we caution you against using any N95 mask in a pandemic or epidemic, or even to stop ordinary colds.

We cannot stress enough the importance of ordering NanoMask right now, before H5N1 or any other pandemic strikes. It's saving lives in Asia right now. More than 2 million Asians are wearing NanoMasks.

Of all the methods available to protect your family, such as antivirals, vaccines, herbs, etc., a NanoMask is the least costly in terms of time and money, and probably the most effective. Don't get caught off guard by a U.S. transportation strike or postal strike, or a thin supply. And don't count on a vaccine, or Tamiflu. Count on NanoMask, it's available right now.

About the author:
John Hart is a science writer, and the author of the popular eBook "How to Protect Your Family Against the Coming Pandemic," available at http://www.urgentebooks.comMr. Hart is also a distributor of NanoMasks at http://www.buynanomask.comA free copy of his eBook comes with each NanoMask order.

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